Sr Research Scientist - Pediatrics Research (20 hrs.)

Many of the greatest minds in cancer research are at MD Anderson. They're here because MD Anderson offers a unique environment that accelerates their ability to end cancer. They collaborate with other cancer experts – in different research areas and with the world's leading cancer doctors. Bright students and trainees contribute further to our dynamic research environment. Discoveries are fueled by vast research support and resources. Tomorrow's medicine is available to our patients first since we have the most cancer clinical trials in the world. These research efforts work in parallel to fight cancer through prevention, early diagnosis, effective therapies and scientific breakthroughs.

SUMMARY

The primary purpose of the Sr Research Scientist (Part-Time) position is to design, initiate and carry out research projects in an independent manner. Design and develop experiments to provide Principal Investigator with desired results and assist Principal Investigator with grant submissions.

The ideal candidate will be have a PhD and skills of human NK cell isolation, expansion, phenotyping via flow cytometry, functional activity analysis and large scale preparation for in vivo efficacy study.

Research Activities 

Coordinate, plan, organize and direct several research projects examining the role of REST in modulating the medulloblastoma microenvironment. Experiments will focus transplanting human cell lines into xenograft and transgenic mouse models; and performing drug screens to identify new epigenetics-based therapeutics. 

Create goals related to experiments, which outline the experimental procedures and data interpretation.
Supervise the design and development of research and equipment needed to obtain the desired result.
Independently modify experimental approach based on these results to achieve specific goals. 
Experimental procedures can include retroviral or lentiviral transduction, high throughput expression and chromatin binding assays, mass spectrometry and other molecular, biochemical and pharmacological approaches, evaluation of intracranial tumors by imaging, pathology, nString and immunohistochemistry.

Publications and Documentation 

Compiles, writes and submits reports to Principal Investigator
Authors abstracts and papers, prepares manuscripts for publication, presents data in scientific meetings.
Assists Principal Investigator with grant applications through data generation, scientific writing and figure generation.

Mentorship and Training  

Trains students, postdoctoral and clinical fellows, and other lab personnel to perform experimental techniques. This may include a wide range of techniques in molecular and cellular biology, light microscopy, imaging and lab software. 

Assigns and reviews work of subordinates, determines specific goals and objectives to be attained and evaluates the resulting data to determine if approach or technique should be modified to achieve desired result.

Communicates and collaborates with staff, faculty and investigators on research projects inside and outside of MD Anderson.

Other duties as assigned.