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Research Laboratory Coordinator - Advanced Spatial Genomics Core
Systems Biology is an interdisciplinary department that is pushing the boundaries of cancer research by integrating technology development, bioengineering, data science, and systems biology. We leverage our massive clinical resources and unmatched access to patient tissue samples to study some of the biggest questions in the cancer field, on topics that include premalignant progression, metastatic dissemination, and therapeutic resistance. Our faculty members represent top-notch scientists working in a wide range of areas of cancer research and commonly use multi-omic approaches to understand the interaction of genotypes and phenotypes at single cell and spatial resolution.
PRIMARY KEY FUNCTIONS:
Core Operations:
- Tissue sectioning: Microtome or Cryostat.
- Tissue Staining – e.g. H&E stain.
- Tissue and cell imaging techniques.
- Prepares libraries for spatial genomic sequencing.
- Performs tissue and cell culture work.
- PCR, qPCR, DNA, RNA isolation and Quality Control.
- Performs next-generation sequencing experiments.
- Develops and tests new spatial genomic technologies for DNA, RNA and epigenomic analysis.
- Runs Xenium and Visium (10X Genomics) experiments.
- Works with data scientists to process and review datasets.
Core Administration:
- Coordinates the overall administration of the CPRIT Spatial Core.
- Supervises assigned laboratory staff. Participates in the selection and evaluation of employees.
- Submits requests for the purchase of consumables and reagents.
- Records non-personnel expenses and program income generated.
- Tracks, communicates and follows up with customer about billing and payments.
- Records and evaluates data in accordance with methods requested.
- Writes protocols and performs molecular biology experiments.
- Assists with administrative responsibilities associated with collecting human tumor samples.
- Maintains records of human samples received, data produced and their location.
- Assists with request to the Technology Task Force (TTF)
Lab Functions & Lab Safety
- Constructs, assembles and operates laboratory apparatus and equipment.
- Assists with the maintenance of laboratory equipment and the overall organization of the lab.
- Ensures laboratory adherence with Environmental Health and Safety policies.
- Other Duties as assigned.
EDUCATION
Required: Bachelor's degree.
Preferred: Master's degree.
EXPERIENCE
Required: Five years of experience in scientific, research or clinical laboratory to include three years in a lead/supervisory capacity. With preferred degree, three years of required experience in a lead/supervisory capacity.
Preferred:
- Molecular biology and genomic techniques, including next-generation sequencing.
- Spatial genomic technologies and histopathological or cytological tissue methods.
- Human tumor samples, including the ability to work with FFPE and frozen tissue section.
- Performing standard laboratory calculations and proficiency with Microsoft Office and Excel.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html
