Research Investigator

MD Anderson’s Cancer Biology department has a long history of being a leader in the field of basic and translational cancer biology research. The department emphasizes the training of students, postdoctoral fellows and clinical fellows in the fundamentals of tumor biology to improve the outcomes of patients with malignancies.

The primary purpose of the Research Investigator is to apply technical expertise and experience to coordinate, design and carry out research projects. This position will assist the principal investigator and postdoctoral fellows with experiments, including data presentation. Experiments include the studies of complex genetically engineered mice, phenotype characterization by tissue analyses and immunohistochemistry, and molecular analyses of tumors and cells. The incumbent is also responsible for maintaining adequate levels of supplies, equipment maintenance and safety oversight for the laboratory. The position requires independent decision making, judgment and organizational skills.

The ideal candidate brings experience with complex molecular and cellular techniques, including extracellular vesicle isolation and characterization, and demonstrates strong organizational skills, independent decision making, and the ability to support various research projects across the institution.

Minimum $28.37 – Midpoint $35.58 – Maximum $42.79 per hour
Work Location: Texas Medical Center

Why Us?
This role directly supports MD Anderson’s mission to end cancer by enabling high‑impact research within a dynamic scientific environment. The Research Investigator will gain exposure to cutting‑edge technologies, contribute to multidisciplinary studies, and develop skills that support long‑term career growth and work‑life balance.

• Employer-paid medical coverage starting day one for employees working 30+ hours/week, plus optional group dental, vision, life, AD&D, and disability insurance.
• Accruals for PTO and Extended Illness Bank, plus paid holidays, wellness, childcare, and other leave options.
• Tuition Assistance Program after six months of service and access to extensive wellness, fitness, and employee resource groups.
• Defined-benefit pension through the Teachers Retirement System, voluntary retirement plans, and employer-paid life and reduced salary protection programs.

Responsibilities

Laboratory Studies
• Perform nucleic acid extraction, PCR, immunoblotting, immunocytochemistry, and immunohistochemistry
• Maintain mammalian tissue culture and perform growth assays
• Conduct molecular analyses of tissues and cells
• Perform gene expression profiling, cloning, and nucleic acid manipulation
• Complete RNAi transfection studies and screening assays
• Conduct flow cytometry
• Present data for analysis to investigators and Core personnel

Experiment Design & Scientific Support
• Assist the principal investigator with experiment design
• Determine goals and objectives for assigned experiments
• Evaluate research data and revise techniques or approaches as needed
• Provide consultation and experimental support to Core users
• Support quality control and quality assurance activities across Core services

Equipment Maintenance
• Maintain laboratory equipment and coordinate repair of malfunctioning units
• Oversee appropriate use of equipment by laboratory personnel
• Ensure proper calibration, cleaning, and documentation of laboratory instruments

Laboratory Organization
• Order and organize laboratory supplies, including tissue culture media
• Monitor consumable expenses and maintain appropriate inventory levels
• Ensure adherence to laboratory cleanliness and safety procedures
• Plan training and work activities for assigned laboratory and research personnel

Project Reporting & Other Duties
• Compile, write, and submit project results to superiors
• Support presentation and reporting needs for Core services
• Perform additional duties as assigned