Research Assistant I - Leukemia - Research

Research Assistant I

The University of Texas MD Anderson Cancer Center is a leading institution focused on cancer care, research, education, and prevention. The Leukemia Research department conducts laboratory-based research focused on understanding the biology of leukemia and developing innovative approaches to improve treatment outcomes. Research activities rely on advanced molecular techniques, cell culture models, and laboratory systems that support translational and preclinical investigations.

The Research Assistant I supports laboratory research activities through tissue culture, molecular biology techniques, laboratory equipment maintenance, and compliance with laboratory safety standards. The Research Assistant I works closely with research staff to maintain cell lines, prepare laboratory materials, perform molecular assays, and support daily laboratory operations. The Research Assistant I plays an important role in ensuring the accuracy, efficiency, and quality of research activities within the laboratory.

The ideal candidate will have experience working in a research laboratory environment and knowledge of tissue culture techniques, molecular biology methods, laboratory equipment maintenance, and laboratory safety practices. Experience with RNA, DNA, and protein analysis, PCR-based assays, and sterile laboratory techniques is highly valued.

Why Us?
This role offers the opportunity to contribute to innovative leukemia research that supports discoveries in cancer biology and treatment. The position provides hands-on experience with molecular techniques, tissue culture systems, and laboratory operations while supporting professional growth within a collaborative research environment.
• Employer-paid medical coverage starting day one for employees working 30+ hours/week, plus optional group dental, vision, life, AD&D, and disability insurance.
• Accruals for PTO and Extended Illness Bank, plus paid holidays, wellness, childcare, and other leave options.
• Tuition Assistance Program after six months of service and access to extensive wellness, fitness, and employee resource groups.
• Defined-benefit pension through the Teachers Retirement System, voluntary retirement plans, and employer-paid life and reduced salary protection programs.

Responsibilities
Tissue Culture
• Maintain and establish tissue culture cell lines using sterile laboratory techniques.
• Observe and identify cell changes using a microscope.
• Determine cell counts using a hemocytometer or Coulter counter.
• Perform colony counts and assess cell viability.
• Prepare sterile media and laboratory solutions.
• Monitor and stock tissue culture supplies to support laboratory operations.
• Prepare cells for cryogenic storage and reestablishment using storage vials, dry ice, and liquid nitrogen.

Molecular Techniques
• Isolate, purify, and analyze RNA, DNA, and proteins.
• Perform hybridization, gel electrophoresis, autoradiography, and ECL staining procedures.
• Conduct PCR reactions and quantitative RT-PCR assays.
• Perform DNA sequencing and assays for signal transducing enzymes.
• Prepare solutions and buffers requiring precise ionic concentrations and pH levels.
• Apply basic knowledge of radioisotope use and safety procedures.

Laboratory Equipment & Maintenance
• Perform routine maintenance of ultra-low freezers and monitor liquid nitrogen, carbon dioxide, and water levels.
• Maintain laboratory equipment, including high-speed centrifuges, pH meters, and microfuges.
• Operate and maintain laboratory equipment according to manufacturer and laboratory procedures.
• Review equipment operation manuals and procedural documentation as needed.

Laboratory Safety & Operations
• Lift and carry items weighing up to 20-25 pounds and transport materials using a roller cart.
• Comply with all institutional safety policies, Universal Precautions, and OSHA standards.
• Handle toxic, hazardous, flammable, radioactive, potentially infectious, and carcinogenic materials safely.
• Utilize appropriate personal protective equipment, including gloves, eye protection, face masks, gowns, and laboratory coats.
• Use fume hoods and biological safety cabinets when required.
• Perform other duties as assigned.