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Institute Research Scientist - Translational Biology

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Research
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Therapeutics Discovery 710621
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115547 Requisition #
Thanks for your interest in the Institute Research Scientist - Translational Biology position. Unfortunately this position has been closed but you can search our 486 open jobs by clicking here.
Education

Required: Bachelor's degree in Biology, Biochemistry, molecular biology, cell biology, enzymology, pharmacology, chemistry or related field. 

Preferred: PhD in Biological Science or Medical degree strongly preferred


Experience

Required: Ten years of relevant research laboratory experience. With Master's degree, eight years of required experience and with PhD, two years of required experience. 

Preferred: At least two years of relevant experience in oncology research in biotech or pharmaceutical environment. 

- Experience with genetic (ie RNAi and cDNAs) and pharmacological (i.e. small molecule inhibitors or antibodies) approaches to study target biology utilizing state of the art  molecular biology and biochemistry methods and assays essential to drive projects.

- Experience working with chemists, in vitro and in vivo pharmacologists to develop and utilize assays in support of the development of small molecules for target validation and as part of compound lead optimization for the development of novel therapeutics is highly desirable.

- A demonstrated track record in the development and implementation of functional genomics strategies to enable systematic investigation into mechanisms of tumorigenesis and drug resistance.

- Broad knowledge of cell culture techniques is required and knowledge of how to utilize in vivo oncology models is desirable. Hands-on experience utilizing genetically engineered mouse models and orthotopic or subcutaneous primary or established tumor cell line xenograft models is desirable.

- Extensive knowledge and experience in key areas of tumor biology including, but not limited to oncogenic signaling, tumor microenvironment, tumor immunology, metabolism, epigenetic deregulation or anti-apoptosis as evidenced by publication in  peer-reviewed journals.

- Strong data analysis skills, ability to interpret results and contribute to the design of follow-up experiments, troubleshoot issues with assay performance, and effectively present results and conclusions to co-workers, collaborators and senior leadership. 




It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html

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