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Institute Research Investigator - Target Discovery and Validation

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Research
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Therapeutics Discovery 710621
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115567 Requisition #
Thanks for your interest in the Institute Research Investigator - Target Discovery and Validation position. Unfortunately this position has been closed but you can search our 472 open jobs by clicking here.
Education
Required: Bachelor's degree in Biology, Biochemistry, molecular biology, cell biology, enzymology, pharmacology, chemistry or related field.  

Preferred: Master's degree in Biology, Biochemistry, molecular biology, cell biology, enzymology, pharmacology, chemistry or related field.  

Experience
Required: Six years experience of relevant research experience in lab. With preferred degree, four years of required experience. 


Preferred: Experience with common tissue culture techniques including viral transduction and DNA/siRNA transfection to generate stable cell lines; experience with complex culture systems including stem cell, co-culture systems, primary tumor cells from clinical or preclinical tumors; common molecular biology skills including Western, ELISA, RNA quantification methods (Q-PCR), DNA cloning (i.e., site directed mutagenesis, protein tagging, shRNA design and validation) and characterization of commercial/custom antibodies; experience (or willingness to work) with vivo models including subcutaneous and orthotopic xenografts or genetically engineered models of cancer; previous experience dosing animals; and, experience developing and utilizing molecular (i.e., Immunofluorescence,  live imaging, ELISA, Western, etc.) and/or functional  (i.e., soft agar, migration, invasion, proliferation, etc.) cell based assays are strongly preferred. Experience using siRNA, inducible shRNA, dominant negative methods to validate targets; as well as experience with utilizing small molecule inhibitors for target and biomarker validation are preferred.  The position requires a highly self-motivated individual, with outstanding organizational skills, the ability to effectively present results and conclusions to co-workers, collaborators and manager. Ability to work well under pressure and drive personal and team objectives that impact critical timelines is expected. A collaborative attitude is essential for this position.

It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html

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