Institute Associate Scientist III - Translational Biology

Preferred: At least one year of relevant research and in a biotech or industry-like environment.

1. The applicant should have knowledge and experience with in vitro cell based models (ie. Soft agar, migration, invasion, etc.) utilizing common methods and reagents (ie. RNAi, dose response curves with small molecule inhibitors, Westerns, ELISAs, flow cytometry, etc.)

2. Experience working with mice using various methods to characterize and evaluate in vivo target and pathway biology as part of drug discovery efforts.  These include protein (immunohistochemistry, IF, RPPA, Western, ELISA), mRNA (RNAseq, nanostring, RNAscope, and PCR), metabolomic (Flux, mass spec), and cellular (Seahorse and flow cytometry) assays is desired.

3. Experience utilizing lentiviral or retroviral systems to perform genetic studies with cancer cell lines is a plus.  These tools and assays will be used to identify and validate novel biomarkers and develop responder ID hypotheses.

4. Experience independently designing and interpreting experimental results is expected.

5. The position requires an accomplished, highly self-motivated individual with outstanding organizational skills, the ability to effectively present results and conclusions to co-workers, collaborators and manager.

It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html